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Acetone is produced and disposed of in the human body through normal metabolic processes. Pregnant women, nursing mothers and children have higher levels of acetone.
Acetone was first produced by alchemists during the late Middle Ages via the dry distillation of metal acetates (e.g., lead acetate, which produced "spirit of Saturn" (since the alchemical symbol for lead was also the astrological symbol for the planet Saturn)).
It is a common building block in organic chemistry.
Familiar household uses of acetone are as the active ingredient in nail polish remover, and as paint thinner. Reproductive toxicity tests show that it has low potential to cause reproductive problems.
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